99mTc-Sestamibi: Clinical Applications by Stefan Guhlke (auth.), Jan Bucerius, Hojjat Ahmadzadehfar, PDF

By Stefan Guhlke (auth.), Jan Bucerius, Hojjat Ahmadzadehfar, Hans-Jürgen Biersack (eds.)

ISBN-10: 3642042325

ISBN-13: 9783642042324

99mTc-sestamibi is a single-photon emission computed tomography (SPECT) radiotracer that's general for the imaging of myocardial perfusion, in addition to various malignant and benign illnesses. 99mTc-Sestamibi – medical purposes presents an in depth and informative evaluation of virtually the entire oncologic and non-oncologic purposes of 99mTc-sestamibi SPECT, together with numerous rather infrequent symptoms. varied disease-related protocols for 99mTc-sestamibi SPECT are offered, and for every ailment a accomplished precis of the correct pathology and epidemiology is supplied. all through, there's a powerful emphasis at the useful points of use of this well known tracer, together with directions for the education of a number of commercially on hand tracer kits. scientific practitioners will locate this e-book to be a useful advisor to the applying and merits of 99mTc-sestamibi SPECT in either the inpatient and the outpatient setting.

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Sample text

Background radioactivity was determined simultaneously within the operative basin after each tissue excision. It was found out that any excised tissue containing more than 20% of background activity in a patient with a positive Sestamibi scan result is a solitary parathyroid adenoma. This technique clearly is a major advance in localizing the parathyroid tissue by a physiologic means rather than by anatomic abnormality and pathologic identification of the enlarged parathyroid gland. If a gland is removed from a patient with pHPT who has a positive Sestamibi scan and it contains more than 20% of the radioactivity that is measurable in the operative basin, that tissue is absolutely a parathyroid adenoma.

Thus, it was concluded that calcium channel blockers reduce the sensitivity of parathyroid Sestamibi-SPECT [44]. In 2004, Kiratli et al. focused on the early phase imaging in hemodialysis patients [45]. It was that Sestamibi-uptake in parathyroid glands was reduced during the early phase imaging in this condition. This paper also discusses the fact that vitamin D supplements can cause diminished uptake of Sestamibi. It is therefore recommended that vitamin D3 metabolites should not be given before parathyroid imaging.

Note: Do not use material if the radiochemical purity is less than 94%. Tc-99m-sestamibi is to be used within 10 h of reconstitution and the container and any unused contents should be disposed in accordance with local requirements for radioactive materials. References 1. Le Petten BVMM (ed) Technescan sestamibi, summary of product characteristics, labelling and package leaflet 2. Gagnon A, Taillefer R, Bavaria G, Leveille J (1991) Fast labeling of technetium-99m-sestamibi with microwave oven heating.

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99mTc-Sestamibi: Clinical Applications by Stefan Guhlke (auth.), Jan Bucerius, Hojjat Ahmadzadehfar, Hans-Jürgen Biersack (eds.)


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